Henoch-Schönlein Purpura (Childhood Immunoglobulin A Vasculitis) Caused by Dental Infection in One of Fraternal Twins: A Case Report

  • Sindy Cornelia Nelwan Department of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
  • Mega Moeharyono Puteri Department of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
  • Udijanto Tedjosasongko Department of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
  • Tania Saskianti Department of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
  • Devi Dharmawan Department of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
Keywords: Henoch-Schönlein purpura, dental infection, fraternal twins

Abstract

Henoch-Schönlein purpura (HSP) is the most common form of vasculitis in children that is clinically characterized by the classic triad of palpable purpura, joint symptoms, and abdominal pain. A 6-year-old girl, one of fraternal twins, was admitted to the Pediatric Department, Universitas Airlangga with fever, rashes on legs and arms and intermittent mild abdominal pain. She had multiple purpuric rashes on her extremities, abdomen and buttocks. Laboratory investigation revealed immunoglobulin A level of 289.6 mg/dL. The patient was diagnosed as HSP vasculitis according to EULAR criteria and treated with intravenous methylprednisolone. She was discharged after three days with normal physical examination and laboratory findings. Intraoral examination showed dental infection in the upper tooth region. The paediatrician suspected a correlation between HSP and her dental infection. The dental infection and genetic susceptibility may be the stimulant factors for the autoimmune reactions that caused HSP vasculitis. Hence, it might be useful to investigate the presence of dental infection in the etiology of HSP cases.

Published
2022-09-29
How to Cite
1.
Nelwan SC, Puteri MM, Tedjosasongko U, Saskianti T, Dharmawan D. Henoch-Schönlein Purpura (Childhood Immunoglobulin A Vasculitis) Caused by Dental Infection in One of Fraternal Twins: A Case Report. Acta Med Philipp [Internet]. 2022Sep.29 [cited 2024Mar.29];56(17). Available from: https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/2185
Section
Articles

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