Spot the Difference: A Case of Hailey-Hailey Disease in a 64-year-old Filipino Female

Authors

  • Raisa Celine R. Rosete Department of Dermatology, Philippine General Hospital, University of the Philippines Manila
  • Juan Paolo David S. Villena Department of Dermatology, Philippine General Hospital, University of the Philippines Manila
  • Mae N. Ramirez-Quizon Department of Dermatology, Philippine General Hospital, University of the Philippines Manila

DOI:

https://doi.org/10.47895/amp.v55i5.2872

Keywords:

Hailey-Hailey Disease, Chronic Benign Familial Pemphigus, Direct Immunofluorescence

Abstract

Hailey-Hailey disease (HHD) is an uncommon acantholytic disorder of the skin. This is a case of a 64-year-old Filipino female with a chronic history of painful and malodorous intertriginous plaques. Histopathologic evaluation showed overlapping features of pemphigus vulgaris and Hailey-Hailey disease. A negative direct immunofluorescence test clinched the diagnosis of Hailey-Hailey disease. The patient was advised regarding preventive measures and treated with topical antibiotics and corticosteroids with improvement of her lesions.

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Published

2021-08-27

How to Cite

1.
Spot the Difference: A Case of Hailey-Hailey Disease in a 64-year-old Filipino Female. Acta Med Philipp [Internet]. 2021 Aug. 27 [cited 2025 Apr. 5];55(5). Available from: https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/2872