Bullous Mastocytosis in a Filipino Infant: A Case Study

  • Blythe N. Ke Department of Dermatology, Philippine General Hospital, University of the Philippines Manila Manila
  • Shahara Abalos-Babaran Department of Dermatology, Philippine General Hospital, University of the Philippines Manila
  • Jay-V James G. Barit Department of Dermatology, Philippine General Hospital, University of the Philippines Manila
  • Mia Katrina R. Gervacio Department of Dermatology, Philippine General Hospital, University of the Philippines Manila
  • Mae N. Ramirez-Quizon Department of Dermatology, Philippine General Hospital, University of the Philippines Manila
Keywords: bullous mastocytosis, cutaneous mastocytosis, diffuse cutaneous mastocytosis

Abstract

Introduction. Mastocytosis is a disease defined by the proliferation of mast cells in organs, most commonly the skin. It may affect any age group but is usually found in children in the first year of life. We present a case of diffuse cutaneous mastocytosis manifesting in the rare bullous form.

Case. A 4-month-old Filipino male presented with multiple bullae on the head, trunk, and extremities after applying chamomile oil. Biopsy of the skin demonstrated numerous mast cells, confirming the diagnosis of bullous mastocytosis. The patient was treated with oral antihistamines and corticosteroids, which was followed by a good response.

Conclusion. Diagnosis of diffuse cutaneous mastocytosis may be challenging due to its rarity. Proper management requires preventive measures, symptomatic treatment, as well as communication of prognosis with the stakeholders.

Published
2021-08-27

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