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A Case of Systematized Epidermal Nevus (Nevus Unius Lateris) in a 20-year-old Filipino Female Treated with Ablative CO2 Laser and Topical Tretinoin

Authors

  • Maria Emilia Ruth V. Eusebio, MD Department of Dermatology, Philippine General Hospital, University of the Philippines Manila https://orcid.org/0009-0009-2188-7994 (##common.opensInNewWindow##)
  • Emy Christine C. Onishi-Limchoa, MD Department of Dermatology, Philippine General Hospital, University of the Philippines Manila
  • Doha Mae Laurisse M. Manalo-Legas, MD Department of Dermatology, Philippine General Hospital, University of the Philippines Manila

DOI:

https://doi.org/10.47895/amp.v58i17.9232

Keywords:

systematized epidermal nevus nevus unius lateris CO2 laser tretinoin retinoid

Abstract

This is a case of a 20-year-old female with no known comorbidities presenting with verrucous plaques arranged in a unilateral blaschkoid distribution at birth. Biopsy was consistent with epidermal nevus hence patient was diagnosed as systematized epidermal nevus, Nevus Unius Lateris type. Gold standard treatment is full thickness surgical excision however, due to the extensive involvement, treatment of this condition remains a challenge. Hence, non-surgical combination of ablative CO2 laser and topical tretinoin 0.1% were done. Thinner lesions (1-3 mm) showed lower recurrence (50%) as compared to thicker lesions (>3 mm) showing 100% recurrence after six months. Hence, another CO2 laser session is needed. Quality of life was measured using the Dermatologic Life Quality Index (DLQI) with noted 35% improvement post-treatment.

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