Predictors of Cognitive Impairment among Filipino Patients with Type 2 Diabetes Mellitus in a Tertiary Government Hospital

Authors

  • Russell Anne Marie L. Carandang, MD Department of Neurosciences, East Avenue Medical Center, East Avenue, Diliman, Quezon City https://orcid.org/0000-0001-8656-4314
  • Marissa T Ong, MD Department of Neurosciences, East Avenue Medical Center, East Avenue, Diliman, Quezon City
  • Roy Alvin J. Malenab, MD Department of Neurosciences, East Avenue Medical Center, East Avenue, Diliman, Quezon City

DOI:

https://doi.org/10.47895/amp.vi0.7648

Keywords:

type 2 diabetes mellitus, cognitive impairment, cognitive dysfunction, dementia, aging, Alzheimer’s Disease

Abstract

Background. Type 2 Diabetes Mellitus (T2DM) patients are predisposed to cognitive decline and dementia. The cooccurrence of the two diseases translate to a higher medical cost. Identification of factors contributing to cognitive impairment is warranted.

Objective. To determine the predictors of cognitive impairment among Filipino patients with Type 2 Diabetes Mellitus.

Methods. This is a cross-sectional analytical study involving Filipino patients diagnosed with T2DM in the outpatient clinic. A total of 171 patients were included and were screened using AD8-P tool.

Results. A total of 171 adult patients were included and screened for cognitive impairment.19.3% were cognitively impaired, with mean age of 59.6 years old (vs. 55.5 years old, p < 0.029), and two-thirds were female. The mean duration of the patient’s diabetes was 11.2 years. After adjusting for confounders and multi-collinearity, the duration of diabetes was significantly associated with cognitive impairment with odds of developing cognitive impairment increasing as the duration reach 10 years above. Those with T2DM for at least ten years were 2.5 times more likely to develop cognitive impairment, holding the age constant. (OR = 2.5, 95% CI – 1.0 to 5.8, p < 0.043).

Conclusion. 19.3% of Filipino patients with Type 2 Diabetes Mellitus in a tertiary government hospital are cognitively impaired and this can occur even in less than 65 years old. The ten years or longer duration of T2DM increases the risk of developing cognitive impairment by 2.5%.

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Published

2024-08-15

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Articles

How to Cite

1.
Predictors of Cognitive Impairment among Filipino Patients with Type 2 Diabetes Mellitus in a Tertiary Government Hospital. Acta Med Philipp [Internet]. 2024 Aug. 15 [cited 2025 Apr. 3];58(14). Available from: https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/7648