Post-COVID-19 Unilateral Upper Lip Numbness: A Case Report

This is a case of a 63-year-old female with post-COVID-19 unilateral upper lip pain and numbness. Neurologic
examination did not reveal any deficits other than deficits on pinprick in the maxillary division (V2) of the
left trigeminal nerve. Brain neuroimaging showed signs of acute inflammation of the left maxillary sinus.
Neuropraxia of the infraorbital nerve, a branch of the trigeminal nerve, was the diagnosis considered.
Reports on trigeminal neurosensory changes following acute sinusitis are few, and isolated trigeminal neuropathy is  rare except in cases of dental disorders. Up to this writing, there have been no reports on post-COVID-19 unilateral upper lip numbness and pain. This study will also serve as a concise review on the correlative neuroanatomy of the trigeminal nerve.