A Systematic Review and Critical Appraisal of the Quality of Studies Looking into the Economic Evaluation of Control Strategies for Soil-Transmitted Helminthiasis and Schistosomiasis

  • Fernando B. Garcia, Jr.
  • Kate Halton-Balcon
  • Nicholas Graves
  • Lydia R. Leonardo
  • Ricardo J. Soares Magalhaes
  • Archie Clements
  • Laith Yakob
Keywords: Economic evaluation, Soil-Transmitted Helminthiasis, Schistosomiasis, systematic review, treatment strategies


Objectives. This research study aims to conduct a systematic review and critical appraisal of the quality of the existing peer-reviewed journal literature looking into the economic evaluation of control strategies used in parasitic diseases (i.e., STH and schistosomiasis).

Methods. Database searches were conducted in Embase, Science Direct, Medline, CINAHL, Econ Lit, and Academic Search Elite, by using search keywords or phrases. Using the predefined inclusion and exclusion criteria, a review of published online articles between January 1990 and December 2012 was conducted. Aside from the set of good practice guidelines in conducting economic evaluations, assessment of the quality of economic evaluations was also carried out following the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist.

Results. Given the inclusion and exclusion criteria set by this review, we systematically reviewed thirteen shortlisted samples of economic analysis studies. The current systematic review shows a wide variety of methodological approaches across studies, including differences in the type of economic evaluation, perspective, time horizon, approach, and adjustments for timing and certainty used.

Conclusions. In general, the economic evaluation studies that have been examined in this review have complied with the set of criteria of good practice in conducting an economic evaluation and that it can be considered helpful in making decisions and in understanding the economics of controlling these parasitic diseases.


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