Trisomy 8 Mosaicism in Two Filipino Children

  • Mary Anne D. Chiong
  • Edsel Allan G. Salonga
  • Eva Maria C. Cutiongco-de la Paz
Keywords: trisomy 8 mosaicism, deep palmar and plantar creases, skeletal abnormalities, hematologic malignancy

Abstract

We describe two Filipino patients with Trisomy 8 mosaicism syndrome. Both had global developmental delay, mental deficiency, facial dysmorphism, skeletal deformities and the characteristic deep plantar and palmar creases. Their phenotype and radiologic features were consistent with the previously reported cases. Hematologic malignancies have recently been found to be associated with this chromosomal abnormality, emphasizing the importance of monitoring for cancer risks.

Published
2008-12-04
How to Cite
1.
Chiong MAD, Salonga EAG, Cutiongco-de la Paz EMC. Trisomy 8 Mosaicism in Two Filipino Children. Acta Med Philipp [Internet]. 2008Dec.4 [cited 2024Mar.29];42(2). Available from: https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/2428
Section
Articles

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